CLIC5

Across TCGA cell cohorts, CLIC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,302 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CLIC5-associated GO terms across cancer lineages are Establishment of endothelial intestinal barrier, Protein localization to cell junction, and Negative regulation of defense response. Each is linked with CLIC5 in more than 8 cancer types. Because this analysis shows association rather than direction, both CLIC5-to-partner and partner-to-CLIC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of endothelial intestinal barrier grouped by CLIC5-low versus CLIC5-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIC5→partner) and Y-score (partner→CLIC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Establishment of endothelial intestinal barrier →	+0.134	+2.482	<.001	<.001	3	8
STOMACH	Protein localization to cell junction →	+0.119	+1.267	.001	.007	3	8
STOMACH	Negative regulation of defense response →	+0.067	+1.421	<.001	<.001	3	8
PANCREAS	Multivesicular body organization →	+0.091	+2.146	.001	<.001	3	8
STOMACH	Small GTPase-mediated signal transduction →	+0.062	+1.389	<.001	.005	3	8
OVARY	Regulation of muscle filament sliding →	+1.300	+2.834	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,302 associations by consensus.

Establishment of endothelial intestinal barrier by CLIC5 expression — OVARY

Explore this box plot interactively →