CLIC4P1

Across TCGA patient cohorts, CLIC4P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,072 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CLIC4P1-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Regulation of cellular response to transforming growth factor beta stimulus, and Ribosome-associated ubiquitin-dependent protein catabolic process. Each is linked with CLIC4P1 in more than 26 cancer types. Because this analysis shows association rather than direction, both CLIC4P1-to-partner and partner-to-CLIC4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle cargo loading grouped by CLIC4P1-low versus CLIC4P1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIC4P1→partner) and Y-score (partner→CLIC4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	COPII-coated vesicle cargo loading →	+0.101	+0.573	<.001	<.001	3	26
STAD	Regulation of cellular response to transforming growth factor beta stimulus →	+0.061	+0.542	<.001	<.001	3	26
UCS	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.066	+0.082	<.001	.001	2	27
STAD	Response to transforming growth factor beta →	+0.065	+0.536	<.001	<.001	3	26
ESCA	Regulation of translational initiation by eIF2 alpha phosphorylation →	+0.085	+0.629	<.001	<.001	3	26
STAD	Actomyosin structure organization →	+0.056	+0.536	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,072 associations by consensus.

COPII-coated vesicle cargo loading by CLIC4P1 expression — ESCA

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