CLIC4P1

Across TCGA pan-cancer cohorts, CLIC4P1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CLIC4P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CLIC4P1 RNA is repressed in tumor relative to normal tissue. In most cancer types CLIC4P1 is over-expressed in tumor, although a few such as KICH and READ show the opposite, repressed pattern.

KICH, KIRC, and HNSC are the cancer types where CLIC4P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLIC4P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−0.199	<.001	4	view →
KIRC	All	All	+0.168	<.001	3	view →
HNSC	Female	IV	+0.165	.018	3	view →
LUAD	All	All	+0.201	.013	2	view →
READ	All	All	−0.167	.021	2	view →
LUSC	All	All	−0.089	.018	2	view →
BLCA	Male	III,IV	−0.324	.037	1	view →
LUSC	All	III,IV	+0.148	.047	1	view →
CHOL	All	All	−0.116	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 8 lineages.

CLIC4P1–KICH

Open the KICH breakdown →