CLIC4

Across TCGA patient cohorts, CLIC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,978 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CLIC4-associated proteins across cancer lineages are FILIP1L, ACTN1, and ITGA5. Each is linked with CLIC4 in more than 7 cancer types. Because this analysis shows association rather than direction, both CLIC4-to-partner and partner-to-CLIC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLIC4 versus FILIP1L in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIC4→partner) and Y-score (partner→CLIC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FILIP1L →	+0.558	+0.579	<.001	<.001	3	8
OV	ACTN1 →	+0.507	+0.917	<.001	<.001	3	7
GBM	ITGA5 →	+0.609	+0.726	<.001	<.001	3	7
OV	LUZP1 →	+0.444	+0.683	<.001	<.001	3	7
BRCA	CALD1 →	+0.643	+0.632	<.001	<.001	3	7
OV	CNN3 →	+0.723	+0.760	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,978 associations by consensus.

CLIC4 vs FILIP1L — OV

Explore this scatter interactively →