CLIC4

Across TCGA cell cohorts, CLIC4 RNA expression is significantly associated with the RNA expression of many other genes, with 11,179 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLIC4-associated genes across cancer lineages are CALU, CUL4B, and VAMP3. Each is linked with CLIC4 in more than 14 cancer types. Because this analysis shows association rather than direction, both CLIC4-to-partner and partner-to-CLIC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLIC4 versus CALU in BONE, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIC4→partner) and Y-score (partner→CLIC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	CALU →	+2.620	+1.255	<.001	<.001	3	15
LIVER	CUL4B →	+1.429	+1.114	<.001	.002	3	15
BLOOD_Myeloma	VAMP3 →	+1.094	+1.228	<.001	<.001	3	15
BREAST	NECAP2 →	+1.156	+2.154	<.001	<.001	2	15
STOMACH	HSPA13 →	+1.681	+2.284	<.001	.001	2	15
BLOOD_Lymphoma	WASF2 →	+1.371	+2.963	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,179 associations by consensus.

CLIC4 vs CALU — BONE

Explore this scatter interactively →