CLHC1

Across TCGA patient cohorts, CLHC1 mutation is significantly associated with the RNA expression of many other genes, with 941 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLHC1-associated genes across cancer lineages are OR8A3P, OR10G1P, and RNU6-964P. Each is linked with CLHC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLHC1-to-partner and partner-to-CLHC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8A3P grouped by CLHC1-low versus CLHC1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLHC1→partner) and Y-score (partner→CLHC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR8A3P →	+0.135	+3.411	<.001	.005	3	2
BLCA	OR10G1P →	+0.030	+4.825	<.001	.002	3	2
LUSC	RNU6-964P →	+0.761	+4.088	<.001	.001	3	2
LUSC	LINC02711 →	+0.028	+4.116	.004	.009	3	2
BLCA	MSANTD2P1 →	+0.031	+3.110	<.001	.004	3	2
BLCA	RPS14P7 →	+0.064	+4.007	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 941 associations by consensus.

OR8A3P by CLHC1 expression — BLCA

Explore this box plot interactively →