CLEC5A

Across TCGA cell cohorts, CLEC5A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,540 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLEC5A-associated GO terms across cancer lineages are Regulation of the force of skeletal muscle contraction, Regulation of skeletal muscle contraction by chemo-mechanical energy conversion, and Neutrophil-mediated killing of fungus. Each is linked with CLEC5A in more than 4 cancer types. Because this analysis shows association rather than direction, both CLEC5A-to-partner and partner-to-CLEC5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of the force of skeletal muscle contraction grouped by CLEC5A-low versus CLEC5A-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC5A→partner) and Y-score (partner→CLEC5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of the force of skeletal muscle contraction →	-0.111	-1.559	<.001	<.001	3	5
BLOOD_Leukemia	Regulation of skeletal muscle contraction by chemo-mechanical energy conversion →	-0.111	-1.559	<.001	<.001	3	5
BLOOD_Leukemia	Neutrophil-mediated killing of fungus →	+1.328	+1.975	<.001	<.001	3	5
LIVER	Negative regulation of appetite by leptin-mediated signaling pathway →	+0.131	+0.018	.001	.004	3	4
OVARY	Proton-transporting two-sector ATPase complex assembly →	-0.063	-0.038	.006	.004	3	4
LUNG_NSCLC_LUSC	Protein sumoylation →	+0.049	+0.063	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,540 associations by consensus.

Regulation of the force of skeletal muscle contraction by CLEC5A expression — BLOOD_Leukemia

Explore this box plot interactively →