CLEC5A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CLEC5A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLEC5A-associated genes across cancer lineages are OR6Q1. Each is linked with CLEC5A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC5A-to-partner and partner-to-CLEC5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6Q1 grouped by CLEC5A-low versus CLEC5A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC5A→partner) and Y-score (partner→CLEC5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR6Q1 →+0.030+6.022<.001.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR6Q1 by CLEC5A expression — LARGE_INTESTINE

Box plot of OR6Q1 in CLEC5A-low vs CLEC5A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration