CLEC4GP1

Across TCGA patient cohorts, CLEC4GP1 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CLEC4GP1-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and Fibroblasts. Each is linked with CLEC4GP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4GP1-to-partner and partner-to-CLEC4GP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by CLEC4GP1-low versus CLEC4GP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4GP1→partner) and Y-score (partner→CLEC4GP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD8+ T-cells →	+0.029	+6.142	<.001	.027	3	1
COAD	CD8+ Tcm →	+0.044	+5.917	<.001	.032	3	1
COAD	Fibroblasts →	+0.066	+5.721	<.001	.036	3	1
COAD	Monocytes →	+0.035	+6.734	<.001	.018	3	1
COAD	Tregs →	+0.122	+6.409	<.001	.023	3	1
COAD	CD4+ naive T-cells →	+0.018	+6.142	.009	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CD8+ T-cells by CLEC4GP1 expression — COAD

Explore this box plot interactively →