Across TCGA patient cohorts, CLEC4C mutation is significantly associated with the RNA expression of many other genes, with 408 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC4C-associated genes across cancer lineages are SIGLEC24P, MIR8082, and TRGJP2. Each is linked with CLEC4C in more than 2 cancer types. Because this analysis shows association rather than direction, both CLEC4C-to-partner and partner-to-CLEC4C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4C→partner) and Y-score (partner→CLEC4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SIGLEC24P →	+0.069	+5.015	<.001	.009	3	3
UCEC	MIR8082 →	+0.399	+2.754	.001	.007	3	2
BLCA	TRGJP2 →	+0.899	+4.266	<.001	.003	3	2
READ	UGT2B24P →	+0.131	+5.219	<.001	.006	3	2
UCEC	CDK8P1 →	+0.092	+3.128	.009	.002	3	2
SKCM	TEKT4P2 →	+0.540	+2.260	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 408 associations by consensus.

Exploration

CLEC4C survival (RNA) · tumor vs normal (RNA) · all CLEC4C data types