CLEC3B

Across TCGA patient cohorts, CLEC3B mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC3B-associated genes across cancer lineages are ERK2, JNK_pT183_Y185, and Myosin-IIa_pS1943. Each is linked with CLEC3B in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC3B-to-partner and partner-to-CLEC3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by CLEC3B-low versus CLEC3B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC3B→partner) and Y-score (partner→CLEC3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.247	+3.000	.014	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.213	-3.000	.015	.036	3	1
UCEC	Myosin-IIa_pS1943 →	+0.255	+2.183	.018	.035	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.513	-3.000	.029	.036	3	1
UCEC	ATM →	-0.499	-3.321	.035	.010	3	1
UCEC	p62 Lck ligand →	+0.358	+3.321	.036	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ERK2 by CLEC3B expression — UCEC

Explore this box plot interactively →