CLEC2B

Across TCGA patient cohorts, CLEC2B protein abundance is significantly associated with the RNA expression of many other genes, with 6,491 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLEC2B-associated genes across cancer lineages are RAP1GAP, VDR, and NBPF3. Each is linked with CLEC2B in more than 3 cancer types. Because this analysis shows association rather than direction, both CLEC2B-to-partner and partner-to-CLEC2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLEC2B versus RAP1GAP in GBM, with a Pearson correlation of -0.94.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC2B→partner) and Y-score (partner→CLEC2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAP1GAP →	-2.696	-0.840	<.001	<.001	3	4
LSCC	VDR →	+0.875	+0.904	<.001	<.001	3	3
HNSC	NBPF3 →	-0.748	-0.583	<.001	.002	3	3
PDAC	FAM83A →	+1.873	+0.632	.002	.009	3	3
GBM	PLXNB1 →	-1.753	-0.829	.002	.002	3	3
GBM	APBB1 →	-1.493	-0.766	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,491 associations by consensus.

CLEC2B vs RAP1GAP — GBM

Explore this scatter interactively →