Across TCGA pan-cancer cohorts, CLEC20A RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CLEC20A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CLEC20A RNA is repressed in tumor relative to normal tissue. In most cancer types CLEC20A is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC and KICH are the cancer types where CLEC20A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLEC20A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.020	<.001	7	view →
KICH	All	II,III,IV	−0.038	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CLEC20A RNA expression & survival · all CLEC20A data types