CLEC1A

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CLEC1A Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CLEC1A data layer compared with 22 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CLEC1A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CLEC1A expression acts as an unfavorable survival marker.

HNSC, LUSC, and COAD are the cancer types where CLEC1A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSMedianAll0.1560.710.00224view →
LUSCOSMedianAll0.0810.818<.0019view →
COADDFSMedianII,III,IV0.0740.744<.0013view →
KIRPDFSMedianAll0.5080.919.0412view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CLEC1A–HNSC (OS)

Kaplan–Meier survival curve for CLEC1A mutant vs wild-type samples in HNSC.

Open the HNSC breakdown →

Exploration