CLEC1A

Across TCGA pan-cancer cohorts, CLEC1A RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CLEC1A’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CLEC1A RNA is repressed in tumor relative to normal tissue. In most cancer types CLEC1A is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, KICH, and KIRC are the cancer types where CLEC1A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLEC1A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−2.343	<.001	11	view →
KICH	All	III,IV	−1.412	<.001	11	view →
KIRC	Female	All	+1.243	<.001	11	view →
KIRP	All	II,III,IV	−1.146	<.001	11	view →
BLCA	Male	All	−1.071	<.001	10	view →
LUSC	Female	All	−2.483	<.001	6	view →
UCEC	All	All	−2.011	<.001	6	view →
BRCA	All	III,IV	−1.290	<.001	6	view →
COAD	All	All	−0.336	.001	5	view →
HNSC	Female	III,IV	+0.825	.008	4	view →
THCA	All	IV	−0.792	.009	2	view →
PRAD	All	All	−0.260	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CLEC1A–LUAD

Open the LUAD breakdown →