CLEC1A

Across TCGA cell cohorts, CLEC1A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLEC1A-associated genes across cancer lineages are DEFA4, H2BC3, and OR6Q1. Each is linked with CLEC1A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC1A-to-partner and partner-to-CLEC1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFA4 grouped by CLEC1A-low versus CLEC1A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC1A→partner) and Y-score (partner→CLEC1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DEFA4 →	+0.032	+4.437	<.001	.004	3	1
LARGE_INTESTINE	H2BC3 →	+0.222	+4.196	<.001	.002	3	1
LARGE_INTESTINE	OR6Q1 →	+0.018	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

DEFA4 by CLEC1A expression — LARGE_INTESTINE

Explore this box plot interactively →