CLEC1A

Across TCGA cell cohorts, CLEC1A mutation is significantly associated with the mutation status of many other genes, with 2,414 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLEC1A-associated genes across cancer lineages are NDUFA10, SDAD1, and AKAP11. Each is linked with CLEC1A in more than 2 cancer types. Because this analysis shows association rather than direction, both CLEC1A-to-partner and partner-to-CLEC1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFA10 grouped by CLEC1A-low versus CLEC1A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC1A→partner) and Y-score (partner→CLEC1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NDUFA10 →	+5.321	+5.894	.002	.002	1	3
LARGE_INTESTINE	SDAD1 →	+3.459	+4.000	<.001	<.001	1	3
LARGE_INTESTINE	AKAP11 →	+2.289	+3.182	.008	.008	1	2
LARGE_INTESTINE	RANBP3 →	+3.874	+4.215	<.001	<.001	1	2
LARGE_INTESTINE	NEXMIF →	+1.874	+3.700	.005	.005	1	2
LARGE_INTESTINE	LAMA3 →	+1.693	+3.506	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,414 associations by consensus.

NDUFA10 by CLEC1A expression — BLOOD_Leukemia

Explore this box plot interactively →