CLEC19A

Across TCGA patient cohorts, CLEC19A mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC19A-associated genes across cancer lineages are RNA5SP405, RNU6-254P, and RNY1P1. Each is linked with CLEC19A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC19A-to-partner and partner-to-CLEC19A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP405 grouped by CLEC19A-low versus CLEC19A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC19A→partner) and Y-score (partner→CLEC19A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP405 →	+0.942	+4.997	<.001	.003	3	1
UCEC	RNU6-254P →	+0.506	+4.109	.005	.004	3	1
UCEC	RNY1P1 →	+0.345	+4.750	<.001	.005	3	1
UCEC	RNA5SP205 →	+0.692	+4.267	<.001	.009	3	1
UCEC	RNA5SP223 →	+0.514	+4.997	<.001	.003	3	1
UCEC	RNU1-28P →	+0.693	+5.069	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

RNA5SP405 by CLEC19A expression — UCEC

Explore this box plot interactively →