CLEC19A

Across TCGA pan-cancer cohorts, CLEC19A RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated CLEC19A data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CLEC19A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CLEC19A expression acts as an unfavorable survival marker, although some lineages such as BLCA and LIHC show a favorable association.

KIRC, LUSC, and BLCA are the cancer types where CLEC19A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.508	0.667	<.001	71	view →
LUSC	OS	Tertile	II,III,IV	0.240	0.442	.003	37	view →
BLCA	OS	Quartile	All	0.591	0.358	.006	36	view →
SKCM	DFS	Tertile	IV	0.016	0.541	.008	24	view →
LGG	OS	Tertile	All	0.724	0.892	.008	19	view →
COAD	DFS	Median	All	0.364	0.586	.011	19	view →
THYM	OS	Tertile	II,III,IV	0.425	0.939	.012	15	view →
THCA	DFS	Tertile	All	0.818	0.940	.005	15	view →
SARC	DFS	Tertile	All	0.120	0.410	.007	15	view →
READ	DFS	Quartile	IV	0.228	0.789	.011	9	view →
UVM	OS	Tertile	III,IV	0.136	0.874	<.001	9	view →
PCPG	DFS	Tertile	All	0.782	0.943	.009	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

CLEC19A–KIRC (OS)

Open the KIRC breakdown →