CLEC19A

Across TCGA cell cohorts, CLEC19A RNA expression is significantly associated with the go_rna of many other GO terms, with 705 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CLEC19A-associated GO terms across cancer lineages are Proteasomal ubiquitin-independent protein catabolic process, Cellular detoxification, and miRNA metabolic process. Each is linked with CLEC19A in more than 4 cancer types. Because this analysis shows association rather than direction, both CLEC19A-to-partner and partner-to-CLEC19A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasomal ubiquitin-independent protein catabolic process grouped by CLEC19A-low versus CLEC19A-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC19A→partner) and Y-score (partner→CLEC19A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Proteasomal ubiquitin-independent protein catabolic process →	+0.055	+0.179	.008	.003	3	5
LUNG_NSCLC_LUSC	Cellular detoxification →	+0.140	+0.339	<.001	.002	3	4
PANCREAS	miRNA metabolic process →	+0.070	+0.060	.005	.006	3	4
PANCREAS	B cell differentiation →	+0.036	+0.067	.005	<.001	3	4
PANCREAS	RNA catabolic process →	+0.036	+0.061	.005	.003	3	4
PANCREAS	mRNA catabolic process →	+0.030	+0.041	.008	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 705 associations by consensus.

Proteasomal ubiquitin-independent protein catabolic process by CLEC19A expression — LUNG_NSCLC_LUAD

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