CLEC18C

Across TCGA pan-cancer cohorts, CLEC18C RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CLEC18C data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CLEC18C RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CLEC18C expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KIRC, HNSC, and THCA are the cancer types where CLEC18C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.694	0.525	<.001	86	view →
HNSC	OS	Tertile	All	0.776	0.639	.003	77	view →
THCA	DFS	Median	III,IV	0.546	0.806	<.001	63	view →
SKCM	DFS	Tertile	IV	0.043	0.529	<.001	60	view →
BRCA	OS	Median	III,IV	0.893	0.779	.004	54	view →
LGG	OS	Median	All	0.721	0.890	<.001	51	view →
THYM	DFS	Tertile	All	0.989	0.804	.002	40	view →
CHOL	OS	Tertile	II,III,IV	0.024	0.601	.025	36	view →
SCLC	OS	Median	II,III,IV	0.731	0.395	.001	30	view →
UCEC	DFS	Quartile	IV	0.848	0.188	<.001	28	view →
GBM	OS	Quartile	All	0.255	0.598	.001	27	view →
ACC	DFS	Tertile	III,IV	0.197	0.673	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CLEC18C–KIRC (DFS)

Open the KIRC breakdown →