CLEC18B

Across TCGA patient cohorts, CLEC18B mutation is significantly associated with the RNA expression of many other genes, with 406 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC18B-associated genes across cancer lineages are WDR7-OT1, USP17L4, and POU5F1P5. Each is linked with CLEC18B in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC18B-to-partner and partner-to-CLEC18B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR7-OT1 grouped by CLEC18B-low versus CLEC18B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC18B→partner) and Y-score (partner→CLEC18B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	WDR7-OT1 →	+0.071	+4.693	.005	.007	3	2
SKCM	USP17L4 →	+0.016	+5.488	<.001	.001	3	1
SKCM	POU5F1P5 →	+0.083	+3.353	.001	.003	3	1
SKCM	RBM17P3 →	+0.021	+4.147	<.001	.008	3	1
SKCM	LINC01808 →	+0.049	+4.897	<.001	.002	3	1
COAD	OR6X1 →	+0.367	+4.951	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 406 associations by consensus.

WDR7-OT1 by CLEC18B expression — COAD

Explore this box plot interactively →