CLEC17A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLEC17A mutation is significantly associated with the RNA expression of many other genes, with 1,210 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC17A-associated genes across cancer lineages are NUDT4B, RPS10-NUDT3, and TAF9. Each is linked with CLEC17A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC17A-to-partner and partner-to-CLEC17A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC17A→partner) and Y-score (partner→CLEC17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCNUDT4B →+0.066+5.108<.001.00832
UCECRPS10-NUDT3 →+0.272+1.942<.001.00432
UCECTAF9 →+0.589+2.321<.001.00132
BRCARPS12P2 →+0.352+4.209<.001.00932
BRCALINC01177 →+0.072+5.571.003.00232
BRCAMIR2467 →+0.785+4.678<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,210 associations by consensus.

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