CLEC12A-AS1

Across TCGA pan-cancer cohorts, CLEC12A-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CLEC12A-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CLEC12A-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLEC12A-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

UVM, SKCM, and LGG are the cancer types where CLEC12A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.370	0.731	<.001	103	view →
SKCM	OS	Median	All	0.402	0.276	.001	26	view →
LGG	OS	Median	All	0.357	0.522	<.001	26	view →
ESCA	DFS	Quartile	III,IV	0.665	0.297	.001	24	view →
LIHC	OS	Tertile	II,III,IV	0.700	0.364	.004	24	view →
STAD	DFS	Tertile	III,IV	0.650	0.366	.002	21	view →
KIRC	OS	Tertile	All	0.573	0.711	.024	15	view →
DLBC	DFS	Median	All	0.317	0.773	.011	15	view →
BLCA	OS	Quartile	III,IV	0.536	0.230	.019	10	view →
ACC	OS	Tertile	II,III,IV	0.873	0.453	.029	10	view →
CHOL	DFS	Quartile	II,III,IV	1.000	0.143	.004	9	view →
LUAD	DFS	Median	III,IV	0.568	0.416	.029	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CLEC12A-AS1–UVM (DFS)

Open the UVM breakdown →