CLDND1

Across TCGA patient cohorts, CLDND1 mutation is significantly associated with the RNA expression of many other genes, with 784 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLDND1-associated genes across cancer lineages are TEX36-AS1, MTCO3P46, and MIR4511. Each is linked with CLDND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDND1-to-partner and partner-to-CLDND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX36-AS1 grouped by CLDND1-low versus CLDND1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDND1→partner) and Y-score (partner→CLDND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TEX36-AS1 →	+0.055	+5.624	<.001	.002	3	2
COAD	MTCO3P46 →	+0.460	+5.602	.001	.004	3	2
LUAD	MIR4511 →	+0.524	+4.584	.003	.001	3	2
SKCM	LINC01082 →	+0.548	+5.254	<.001	.001	3	1
UCEC	RPSAP57 →	+0.050	+2.639	<.001	<.001	3	1
UCEC	H3Y1 →	+0.582	+1.874	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 784 associations by consensus.

TEX36-AS1 by CLDND1 expression — SKCM

Explore this box plot interactively →