CLDN3

Across TCGA patient cohorts, CLDN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,102 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CLDN3-associated proteins across cancer lineages are CLDN3_S209, REPIN1, and CAPS. Each is linked with CLDN3 in more than 6 cancer types. Because this analysis shows association rather than direction, both CLDN3-to-partner and partner-to-CLDN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLDN3 versus CLDN3_S209 in LUAD, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN3→partner) and Y-score (partner→CLDN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CLDN3_S209 →	+1.299	+1.577	<.001	<.001	3	7
HNSC	REPIN1 →	+0.405	+0.998	<.001	<.001	3	4
LSCC	CAPS →	+0.831	+1.257	<.001	<.001	3	4
LSCC	CGN_S338 →	+0.751	+1.336	<.001	<.001	3	4
HNSC	CLDN3_Y198 →	+1.601	+3.393	.003	.004	3	4
LUAD	ABHD11 →	+0.570	+1.558	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,102 associations by consensus.

CLDN3 vs CLDN3_S209 — LUAD

Explore this scatter interactively →