CLDN15

Across TCGA patient cohorts, CLDN15 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,045 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLDN15-associated proteins across cancer lineages are GTF2I, MEPCE, and LARP7. Each is linked with CLDN15 in more than 5 cancer types. Because this analysis shows association rather than direction, both CLDN15-to-partner and partner-to-CLDN15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLDN15 versus GTF2I in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN15→partner) and Y-score (partner→CLDN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GTF2I →	+0.357	+0.442	<.001	<.001	3	6
LSCC	MEPCE →	+0.343	+0.512	<.001	<.001	3	6
LSCC	LARP7 →	+0.290	+0.397	<.001	<.001	3	5
LSCC	ZNF655 →	+0.408	+0.455	<.001	.003	3	4
GBM	WIZ →	+0.315	+0.301	<.001	.004	3	4
HNSC	ZKSCAN1 →	+0.415	+0.822	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,045 associations by consensus.

CLDN15 vs GTF2I — LSCC

Explore this scatter interactively →