CLDN15

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CLDN15 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLDN15-associated genes across cancer lineages are CCDC195. Each is linked with CLDN15 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDN15-to-partner and partner-to-CLDN15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC195 grouped by CLDN15-low versus CLDN15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN15→partner) and Y-score (partner→CLDN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECCDC195 →+0.044+4.467.003.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CCDC195 by CLDN15 expression — LARGE_INTESTINE

Box plot of CCDC195 in CLDN15-low vs CLDN15-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration