CLDN10

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLDN10 protein abundance is significantly associated with the RNA expression of many other genes, with 4,871 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CLDN10-associated genes across cancer lineages are RHBDL1, CCDC93, and DSPP. Each is linked with CLDN10 in more than 2 cancer types. Because this analysis shows association rather than direction, both CLDN10-to-partner and partner-to-CLDN10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLDN10 versus RHBDL1 in OV, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN10→partner) and Y-score (partner→CLDN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRHBDL1 →-1.042-1.672.001.00132
OVCCDC93 →-0.741-1.223.006.00432
GBMDSPP →-0.794-0.724.001.00832
OVPTPRR →+1.568+1.771<.001<.00132
OVSLC30A2 →+1.922+1.800<.001<.00132
LUADANKRD20A8P →-0.393-1.626.007<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,871 associations by consensus.

CLDN10 vs RHBDL1 — OV

Per-sample scatter of CLDN10 vs RHBDL1 in OV (Pearson r = -0.44).

Explore this scatter interactively →

Exploration