CLDN10

Across TCGA cell cohorts, CLDN10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,519 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLDN10-associated GO terms across cancer lineages are Ribonucleotide metabolic process, Negative regulation of syncytium formation by plasma membrane fusion, and Cytoplasmic translation. Each is linked with CLDN10 in more than 6 cancer types. Because this analysis shows association rather than direction, both CLDN10-to-partner and partner-to-CLDN10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribonucleotide metabolic process grouped by CLDN10-low versus CLDN10-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN10→partner) and Y-score (partner→CLDN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Ribonucleotide metabolic process →	+0.050	+2.443	<.001	<.001	3	7
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.123	+1.408	<.001	.007	3	7
BREAST	Cytoplasmic translation →	+0.070	+0.783	<.001	.005	3	6
BREAST	Negative regulation of mRNA splicing, via spliceosome →	+0.069	+1.092	.004	.008	3	6
BREAST	Regulation of myoblast fusion →	+0.107	+1.391	<.001	.008	3	6
BREAST	Striated muscle contraction →	+0.054	+0.793	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,519 associations by consensus.

Ribonucleotide metabolic process by CLDN10 expression — PANCREAS

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