CLCN7

Across TCGA patient cohorts, CLCN7 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,231 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CLCN7-associated proteins across cancer lineages are CDR2_S311, MARK3, and NOSTRIN. Each is linked with CLCN7 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLCN7-to-partner and partner-to-CLCN7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLCN7 versus CDR2_S311 in LUAD, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCN7→partner) and Y-score (partner→CLCN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDR2_S311 →	+0.369	+0.464	<.001	<.001	3	4
LSCC	MARK3 →	-0.237	-0.356	.006	.002	3	3
CCRCC	NOSTRIN →	-0.464	-0.337	.003	.002	3	3
LSCC	HSP90AB1 →	+0.200	+0.262	<.001	.001	3	3
LSCC	CDC42BPB →	-0.228	-0.413	.002	.001	3	3
LUAD	AGAP1_T836 →	-0.541	-0.495	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,231 associations by consensus.

CLCN7 vs CDR2_S311 — LUAD

Explore this scatter interactively →