CLCC1

Across TCGA cell cohorts, CLCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,035 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLCC1-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, IMP salvage, and ERAD pathway. Each is linked with CLCC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both CLCC1-to-partner and partner-to-CLCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by CLCC1-low versus CLCC1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCC1→partner) and Y-score (partner→CLCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Zinc ion import into Golgi lumen →	+0.129	+0.972	.002	<.001	2	11
LUNG_NSCLC_LUAD	IMP salvage →	+0.183	+0.751	<.001	<.001	3	10
CNS	ERAD pathway →	+0.078	+0.598	<.001	<.001	2	11
BLOOD_Myeloma	Cytosol to Golgi apparatus transport →	+0.142	+0.967	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	DNA damage tolerance →	+0.105	+1.101	<.001	<.001	3	9
OVARY	Positive regulation of translational initiation →	+0.087	+0.694	.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,035 associations by consensus.

Zinc ion import into Golgi lumen by CLCC1 expression — BLOOD_Myeloma

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