CLCC1

Across TCGA pan-cancer cohorts, CLCC1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CLCC1 data layer compared with 5 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher CLCC1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLCC1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

KICH, KIRC, and READ are the cancer types where CLCC1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Quartile	II,III,IV	0.317	0.944	<.001	108	view →
KIRC	OS	Median	All	0.710	0.559	<.001	91	view →
READ	OS	Tertile	All	0.959	0.378	<.001	83	view →
CESC	DFS	Tertile	All	0.744	0.873	.002	60	view →
LGG	DFS	Median	All	0.663	0.815	<.001	54	view →
COAD	OS	Median	All	0.750	0.567	<.001	47	view →
BLCA	DFS	Tertile	All	0.240	0.533	.003	43	view →
HNSC	OS	Quartile	All	0.170	0.558	<.001	42	view →
ACC	DFS	Tertile	All	0.258	0.659	<.001	39	view →
LIHC	OS	Tertile	All	0.674	0.856	.001	29	view →
LUSC	DFS	Median	III,IV	0.545	0.779	.005	18	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CLCC1–KICH (DFS)

Open the KICH breakdown →