CLCC1

Across TCGA cell cohorts, CLCC1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLCC1-associated genes across cancer lineages are SLC5A5, PITX3, and ASB18. Each is linked with CLCC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLCC1-to-partner and partner-to-CLCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A5 grouped by CLCC1-low versus CLCC1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCC1→partner) and Y-score (partner→CLCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC5A5 →	+0.310	+2.822	<.001	.005	3	1
LARGE_INTESTINE	PITX3 →	+0.172	+3.374	<.001	.005	3	1
LARGE_INTESTINE	ASB18 →	+0.046	+2.938	.004	.007	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1
LARGE_INTESTINE	PFN3 →	+0.090	+2.882	<.001	.005	3	1
LARGE_INTESTINE	BAAT →	+0.433	+3.273	<.001	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

SLC5A5 by CLCC1 expression — LARGE_INTESTINE

Explore this box plot interactively →