CLCC1

Across TCGA cell cohorts, CLCC1 mutation is significantly associated with the mutation status of many other genes, with 2,724 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLCC1-associated genes across cancer lineages are WNK1, TEAD2, and CGN. Each is linked with CLCC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CLCC1-to-partner and partner-to-CLCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WNK1 grouped by CLCC1-low versus CLCC1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCC1→partner) and Y-score (partner→CLCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	WNK1 →	+2.779	+4.326	.006	.006	1	3
BLOOD_Lymphoma	TEAD2 →	+5.014	+5.584	.003	.003	1	3
BLOOD_Leukemia	CGN →	+3.672	+5.083	.001	.001	1	3
BLOOD_Leukemia	DIP2C →	+2.672	+4.225	.008	.008	1	3
BLOOD_Leukemia	CLDN23 →	+6.479	+6.479	<.001	<.001	1	3
BLOOD_Lymphoma	JCAD →	+4.014	+4.969	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,724 associations by consensus.

WNK1 by CLCC1 expression — BLOOD_Leukemia

Explore this box plot interactively →