CLCA4

Across TCGA cell cohorts, CLCA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 792 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CLCA4-associated GO terms across cancer lineages are Positive regulation of collagen biosynthetic process, Nuclear receptor-mediated steroid hormone signaling pathway, and Steroid hormone receptor signaling pathway. Each is linked with CLCA4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLCA4-to-partner and partner-to-CLCA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of collagen biosynthetic process grouped by CLCA4-low versus CLCA4-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCA4→partner) and Y-score (partner→CLCA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of collagen biosynthetic process →	-0.086	-0.117	.001	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Nuclear receptor-mediated steroid hormone signaling pathway →	+0.070	+0.709	.003	.007	3	4
UPPER_AERODIGESTIVE_TRACT	Steroid hormone receptor signaling pathway →	+0.070	+0.709	.003	.007	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic cell cycle, embryonic →	+0.182	+0.774	.001	.007	3	3
URINARY_TRACT	Glycerol transmembrane transport →	+1.944	+1.458	<.001	.006	3	3
URINARY_TRACT	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.069	+1.536	.006	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 792 associations by consensus.

Positive regulation of collagen biosynthetic process by CLCA4 expression — BLOOD_Lymphoma

Explore this box plot interactively →