CLCA4-AS1

Across TCGA pan-cancer cohorts, CLCA4-AS1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CLCA4-AS1 data layer compared with 17 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CLCA4-AS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CLCA4-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCEC show a favorable association.

HNSC, OV, and GBM are the cancer types where CLCA4-AS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.156	0.751	<.001	48	view →
OV	DFS	Median	II,III,IV	0.214	0.541	.023	18	view →
GBM	OS	Median	All	0.079	0.415	.003	9	view →
LUAD	OS	Median	II,III,IV	0.245	0.749	.019	9	view →
SKCM	OS	Median	II,III,IV	1.000	0.306	.021	8	view →
UCEC	OS	Median	All	0.973	0.865	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CLCA4-AS1–HNSC (OS)

Open the HNSC breakdown →