CLCA2

Across TCGA patient cohorts, CLCA2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,370 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CLCA2-associated genes across cancer lineages are TM4SF19, MBOAT1, and AMMECR1. Each is linked with CLCA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CLCA2-to-partner and partner-to-CLCA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLCA2 versus TM4SF19 in HNSC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCA2→partner) and Y-score (partner→CLCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TM4SF19 →	+0.913	+0.783	.008	.001	3	3
BRCA	MBOAT1 →	-1.241	-1.153	<.001	<.001	3	3
BRCA	AMMECR1 →	+0.674	+1.118	.001	<.001	3	3
HNSC	PERP →	+1.009	+1.177	.001	<.001	3	3
BRCA	FRMD4B →	+0.621	+1.102	<.001	<.001	3	3
BRCA	SDC1 →	+1.116	+1.143	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,370 associations by consensus.

CLCA2 vs TM4SF19 — HNSC

Explore this scatter interactively →