CKS2

Across TCGA patient cohorts, CKS2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,185 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CKS2-associated genes across cancer lineages are KIF11, CENPE, and KIF20B. Each is linked with CKS2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CKS2-to-partner and partner-to-CKS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CKS2 versus KIF11 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CKS2→partner) and Y-score (partner→CKS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF11 →	+0.879	+0.574	.001	<.001	3	4
UCEC	CENPE →	+0.797	+0.472	.002	.007	3	4
BRCA	KIF20B →	+0.693	+0.471	<.001	<.001	3	4
LSCC	CEP76 →	+0.609	+0.499	.001	<.001	3	3
UCEC	CEP55 →	+1.116	+0.672	<.001	<.001	3	3
BRCA	ZNF367 →	+0.835	+0.354	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,185 associations by consensus.

CKS2 vs KIF11 — UCEC

Explore this scatter interactively →