CKS1BP4

Across TCGA pan-cancer cohorts, CKS1BP4 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated CKS1BP4 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher CKS1BP4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CKS1BP4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

MESO, SKCM, and HNSC are the cancer types where CKS1BP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.044	0.610	<.001	87	view →
SKCM	OS	Tertile	All	0.430	0.280	.001	51	view →
HNSC	OS	Tertile	II,III,IV	0.514	0.313	.006	39	view →
READ	DFS	Tertile	III,IV	0.911	0.290	.016	39	view →
BLCA	DFS	Tertile	IV	0.329	0.494	.014	30	view →
ACC	DFS	Median	II,III,IV	0.355	0.652	.002	30	view →
THYM	DFS	Tertile	II,III,IV	0.701	0.961	.003	24	view →
LUSC	DFS	Median	III,IV	0.493	0.732	.005	20	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
OV	OS	Median	II,III,IV	0.811	0.872	.006	18	view →
CHOL	OS	Tertile	All	0.258	0.688	.014	9	view →
LGG	OS	Tertile	All	0.845	0.936	.005	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

CKS1BP4–MESO (OS)

Open the MESO breakdown →