CKS1BP4

Across TCGA pan-cancer cohorts, CKS1BP4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CKS1BP4’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where CKS1BP4 RNA is repressed in tumor relative to normal tissue. In most cancer types CKS1BP4 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

ESCA, KIRP, and LUSC are the cancer types where CKS1BP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CKS1BP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	−0.270	.001	2	view →
KIRP	Female	All	+0.229	.015	1	view →
LUSC	Male	All	+0.077	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

CKS1BP4–ESCA

Open the ESCA breakdown →