CKS1B

Across TCGA patient cohorts, CKS1B mutation is significantly associated with the RNA expression of many other genes, with 163 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CKS1B-associated genes across cancer lineages are RNU6-784P, SEC63P2, and MIR6777. Each is linked with CKS1B in more than 1 cancer types. Because this analysis shows association rather than direction, both CKS1B-to-partner and partner-to-CKS1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-784P grouped by CKS1B-low versus CKS1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CKS1B→partner) and Y-score (partner→CKS1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-784P →	+0.271	+3.350	.002	.001	3	2
UCEC	SEC63P2 →	+0.136	+3.193	<.001	.001	3	2
BRCA	MIR6777 →	+0.471	+5.575	.001	.004	3	1
BRCA	RNU7-179P →	+0.455	+5.230	<.001	.007	3	1
BRCA	OR5BN2P →	+0.036	+7.471	<.001	.008	3	1
UCEC	TBX6 →	+0.960	+3.223	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 163 associations by consensus.

RNU6-784P by CKS1B expression — UCEC

Explore this box plot interactively →