CKS1B

Across TCGA pan-cancer cohorts, CKS1B RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of CKS1B’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where CKS1B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CKS1B is over-expressed in tumor, although a few such as KICH and PRAD show the opposite, repressed pattern.

BLCA, HNSC, and KIRC are the cancer types where CKS1B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CKS1B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+2.295	<.001	12	view →
HNSC	Male	IV	+1.993	<.001	12	view →
KIRC	Male	IV	+1.102	<.001	12	view →
LUAD	Male	III,IV	+2.098	<.001	11	view →
COAD	Female	II,III,IV	+1.438	<.001	11	view →
STAD	Female	All	+1.935	<.001	9	view →
LIHC	Male	All	+1.703	<.001	9	view →
KIRP	All	III,IV	+0.958	<.001	9	view →
LUSC	Male	II,III,IV	+2.375	<.001	8	view →
READ	All	All	+1.075	<.001	7	view →
KICH	Female	II,III,IV	−1.924	<.001	6	view →
UCEC	All	II,III,IV	+1.365	<.001	6	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

CKS1B–BLCA

Open the BLCA breakdown →