CKS1B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CKS1B mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible CKS1B-associated genes across cancer lineages are MPP and Th2 cells. Each is linked with CKS1B in more than 1 cancer types. Because this analysis shows association rather than direction, both CKS1B-to-partner and partner-to-CKS1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by CKS1B-low versus CKS1B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CKS1B→partner) and Y-score (partner→CKS1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCMPP →+0.012+4.694.015.01431
UCECTh2 cells →+0.297+3.169.002.02011
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MPP by CKS1B expression — LUSC

Box plot of MPP in CKS1B-low vs CKS1B-high samples in LUSC.

Explore this box plot interactively →

Exploration