CKS1B

Across TCGA cell cohorts, CKS1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,092 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CKS1B-associated GO terms across cancer lineages are Positive regulation of cell cycle phase transition, Protein localization to condensed chromosome, and Nuclear DNA replication. Each is linked with CKS1B in more than 17 cancer types. Because this analysis shows association rather than direction, both CKS1B-to-partner and partner-to-CKS1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle phase transition grouped by CKS1B-low versus CKS1B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKS1B→partner) and Y-score (partner→CKS1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle phase transition →	+0.123	+1.323	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.192	+1.486	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Nuclear DNA replication →	+0.148	+1.460	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cell cycle DNA replication →	+0.151	+1.481	<.001	<.001	3	18
BLOOD_Lymphoma	Spindle elongation →	+0.220	+1.190	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Metaphase chromosome alignment →	+0.123	+1.267	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,092 associations by consensus.

Positive regulation of cell cycle phase transition by CKS1B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →