CKM

Across TCGA patient cohorts, CKM RNA expression is significantly associated with the protein abundance of many other proteins, with 8,585 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CKM-associated proteins across cancer lineages are TGFBI, RPL4, and RPS8. Each is linked with CKM in more than 2 cancer types. Because this analysis shows association rather than direction, both CKM-to-partner and partner-to-CKM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CKM versus TGFBI in CCRCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CKM→partner) and Y-score (partner→CKM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TGFBI →	+0.470	+0.105	.002	.003	3	3
COAD	RPL4 →	-0.237	-0.166	<.001	.004	3	3
CCRCC	RPS8 →	-0.200	-0.136	.008	.003	3	3
UCEC	RREB1_S1219 →	-0.433	-0.336	.002	.002	3	2
UCEC	RTN1_S352 →	+1.018	+0.249	<.001	.008	2	3
UCEC	COBL_S815 →	-0.562	-0.265	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,585 associations by consensus.

CKM vs TGFBI — CCRCC

Explore this scatter interactively →