Across TCGA cell cohorts, CKLF RNA expression is significantly associated with the go_rna of many other GO terms, with 2,623 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CKLF-associated GO terms across cancer lineages are Deoxyribose phosphate biosynthetic process, 2'-deoxyribonucleotide biosynthetic process, and DTMP biosynthetic process. Each is linked with CKLF in more than 7 cancer types. Because this analysis shows association rather than direction, both CKLF-to-partner and partner-to-CKLF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKLF→partner) and Y-score (partner→CKLF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Deoxyribose phosphate biosynthetic process →	+0.120	+0.873	.001	.002	3	8
BONE	2'-deoxyribonucleotide biosynthetic process →	+0.120	+0.873	.001	.002	3	8
SKIN	DTMP biosynthetic process →	+0.093	+0.358	.001	.007	3	8
SKIN	Pyrimidine deoxyribonucleoside monophosphate biosynthetic process →	+0.093	+0.358	.001	.007	3	8
OESOPHAGUS	Regulation of DNA damage checkpoint →	+0.086	+0.987	.001	.001	2	8
SKIN	DNA replication, synthesis of primer →	+0.114	+0.659	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,623 associations by consensus.

Exploration

CKLF survival (RNA) · tumor vs normal (RNA) · all CKLF data types