CKB

Across TCGA patient cohorts, CKB mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CKB-associated genes across cancer lineages are CD8+ T-cells and Monocytes. Each is linked with CKB in more than 1 cancer types. Because this analysis shows association rather than direction, both CKB-to-partner and partner-to-CKB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by CKB-low versus CKB-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CKB→partner) and Y-score (partner→CKB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CD8+ T-cells →	+0.076	+5.015	<.001	.009	3	1
COAD	Monocytes →	+0.035	+5.149	<.001	.036	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ T-cells by CKB expression — HNSC

Explore this box plot interactively →