CKAP5

Across TCGA pan-cancer cohorts, CKAP5 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CKAP5 data layer compared with 24 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CKAP5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CKAP5 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where CKAP5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	1.000	0.869	.008	8	view →
LUAD	DFS	Median	All	0.495	0.745	.011	6	view →
CCRCC	DFS	Quartile	All	0.560	0.971	.025	4	view →
HNSC	OS	Quartile	IV	0.777	0.474	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CKAP5–LSCC (DFS)

Open the LSCC breakdown →