CKAP5

Across TCGA cell cohorts, CKAP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,975 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CKAP5-associated GO terms across cancer lineages are Regulation of mitotic metaphase/anaphase transition, Chromosome condensation, and Mitotic sister chromatid segregation. Each is linked with CKAP5 in more than 18 cancer types. Because this analysis shows association rather than direction, both CKAP5-to-partner and partner-to-CKAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic metaphase/anaphase transition grouped by CKAP5-low versus CKAP5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKAP5→partner) and Y-score (partner→CKAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of mitotic metaphase/anaphase transition →	+0.130	+1.209	<.001	<.001	3	19
PANCREAS	Chromosome condensation →	+0.162	+0.949	<.001	.001	3	19
UPPER_AERODIGESTIVE_TRACT	Mitotic sister chromatid segregation →	+0.126	+0.980	.001	.001	3	19
PANCREAS	Mitotic chromosome condensation →	+0.180	+1.144	<.001	<.001	3	19
BREAST	Regulation of metaphase/anaphase transition of cell cycle →	+0.124	+1.198	<.001	<.001	3	19
BONE	Mitotic spindle elongation →	+0.261	+0.716	.001	.002	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,975 associations by consensus.

Regulation of mitotic metaphase/anaphase transition by CKAP5 expression — BREAST

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